Nickel-catalyzed transamidation of aliphatic amide derivatives† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c7sc01980g

Nickel-catalyzed transamidation of aliphatic amide derivatives.

Transamidation, or the conversion of one amide to another, is a long-standing challenge in organic synthesis. Although notable progress has been made in the transamidation of primary amides, the transamidation of secondary amides has remained underdeveloped, especially when considering aliphatic substrates. Herein, we report a two-step approach to achieve the transamidation of secondary aliphat...

Oxalyl amide assisted palladium-catalyzed synthesis of pyrrolidones via carbonylation of γ-C(sp3)–H bonds of aliphatic amine substrates† †Electronic supplementary information (ESI) available: Experimental procedures, characterization data for all new compounds. CCDC 1048649. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c5sc00519a

Amide synthesis via nickel-catalysed reductive aminocarbonylation of aryl halides with nitroarenes† †Electronic supplementary information (ESI) available: Experimental and spectra data. See DOI: 10.1039/c7sc03950f

Introducing unactivated acyclic internal aliphatic olefins into a cobalt catalyzed allylic selective dehydrogenative Heck reaction† †Electronic supplementary information (ESI) available. CCDC 1507233. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c7sc01204g Click here for additional data file. Click here for additional data file.

Unactivated acyclic internal aliphatic olefins are often found to be unreactive in conventional alkenylation reactions. To address this problem, a cobalt catalyzed allylic selective dehydrogenative Heck reaction with internal aliphatic olefins has been developed. The method is highly regioand stereoselective, the conditions are mild and a wide variety of functional groups can be tolerated. Rema...

Synthesis of (diarylmethyl)amines using Ni-catalyzed arylation of C(sp3)–H bonds† †Electronic supplementary information (ESI) available: Full experimental and optimization details, characterization of all the synthesized products. See DOI: 10.1039/c5sc01589h